Thursday, May 23, 2013

Sun's blood pressure benefits 'may outdo cancer risks' | BBC News

http://www.bbc.co.uk/news/uk-scotland-edinburgh-east-fife-22433359

The health benefits of exposing skin to sunlight may far outweigh the risk of developing skin cancer, according to scientists.

Edinburgh University researchers found skin exposed to UV rays
released a compound that lowers blood pressure
Edinburgh University research suggests sunlight helps reduce blood pressure, cutting heart attack and stroke risks and even prolonging life.

UV rays were found to release a compound that lowers blood pressure.

Researchers said more studies would be carried out to determine if it is time to reconsider advice on skin exposure.

Heart disease and stroke linked to high blood pressure are estimated to lead to about 80 times more deaths than those from skin cancer in the UK.


Production of the pressure-reducing compound, nitric oxide, is separate from the body's manufacture of vitamin D, which rises after exposure to sunshine.

Researchers said that until now vitamin D production had been considered the sole benefit of the sun to human health.

During the research, dermatologists studied the blood pressure of 24 volunteers under UV and heat lamps.

In one session, the volunteers were exposed to both UV rays and the heat of the lamps.

In the other, the UV rays were blocked so that only the heat affected the skin.

The results showed that blood pressure dropped significantly for an hour after exposure to UV rays, but not after the heat-only sessions.

Scientists said that this suggested it was the sun's UV rays that brought health benefits.

The volunteers' vitamin D levels remained unaffected in both sessions.
'Reconsider our advice'
Dr Richard Weller, a senior lecturer in dermatology at Edinburgh University, said: "We suspect that the benefits to heart health of sunlight will outweigh the risk of skin cancer.

"The work we have done provides a mechanism that might account for this, and also explains why dietary vitamin D supplements alone will not be able to compensate for lack of sunlight.

"We now plan to look at the relative risks of heart disease and skin cancer in people who have received different amounts of sun exposure.

"If this confirms that sunlight reduces the death rate from all causes, we will need to reconsider our advice on sun exposure."

The study will be presented on Friday in Edinburgh at the world's largest gathering of skin experts. The International Investigative Dermatology conference starts on Wednesday and runs until Saturday.

Sunshine vitamin 'may treat asthma' | BBC News

http://www.bbc.co.uk/news/health-22570859


The amount of time asthma patients spend soaking up the sun may have an impact on the illness, researchers have suggested.

A team at King's College London said low levels of vitamin D, which is made by the body in sunlight, was linked to a worsening of symptoms.

Its latest research shows the vitamin calms an over-active part of the immune system in asthma.

However, treating patients with vitamin D has not yet been tested.

People with asthma can find it hard to breathe when their airways become inflamed, swollen and narrowed.

Most people are treated with steroids, but the drugs do not work for all.
Sunshine
"We know people with high levels of vitamin D are better able to control their asthma - that connection is quite striking," said researcher Prof Catherine Hawrylowicz.

Her group investigated the impact of the vitamin on a chemical in the body, interleukin-17. It is a vital part of the immune system and helps to fight off infections.

However, it can cause problems when levels get too high and has been strongly implicated in asthma.

In this study, published in the Journal of Allergy and Clinical Immunology, vitamin D was able to lower levels of interleukin-17 when it was added to blood samples taken from 28 patients.

The team is now conducting clinical trials to see if giving the sunshine vitamin to patients could ease their symptoms. They are looking at patients who do not respond to steroids as they produce seven times more interleukin-17 than other patients.

Prof Catherine Hawrylowicz told the BBC: "We think that treating people with vitamin D could make steroid-resistant patients respond to steroids or let those who can control their asthma take less steroids."

She said a culture of covering up in the sun and using sun cream may have increased asthma rates, but "it is a careful message because too much sun is bad for you".

Malayka Rahman, from the charity Asthma UK, said: "For the majority of people with asthma, current available medicines are an effective way of managing the condition but we know that they don't work for everyone, which is why research into new treatments is vital.

"We also know that many people with asthma have concerns about the side effects of their medicines so if vitamin D is shown to reduce the amount of medicines required, this would have an enormous impact on people's quality of life.

"We look forward to the results of the clinical trial."